NSC 625987 是一种特异性和高亲和力的 CDK4 抑制剂,对 CDK4:cyclin D1 的 IC50 为 0.2 μM。 NSC 625987 对 CDK4 的选择性比 CDK2 高 500 倍以上。
Cas No. | 141992-47-4 |
化学名 | 1,4-dimethoxyacridine-9(10H)-thione |
Canonical SMILES | S=C1C(C(NC2=CC=CC=C21)=C3OC)=C(C=C3)OC |
分子式 | C15H13NO2S |
分子量 | 271.33 |
溶解度 | <27.13mg/ml in DMSO |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |