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4-Hydroxy-2-methylbenzenesulfonic acid ammonium
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
4-Hydroxy-2-methylbenzenesulfonic acid ammonium图片
包装与价格：
包装价格(元)
50mg电议
100mg电议

产品介绍
4-Hydroxy-2-methylbenzenesulfonicacidammonium是Policresulen的杂质。Policresulen是一种有效的NS2B/NS3蛋白酶抑制剂，IC50为0.48μg/mL。Policresulen有效抑制DENV2病毒在BHK-21细胞中的复制，IC50为4.99μg/mL。Policresulen是蛋白酶的竞争性抑制剂，并轻微影响蛋白酶的稳定性。
Canonical SMILESO=S(C1=CC=C(O)C=C1C)(O)=O.N
分子式C7H11NO4S
分子量205.23
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4-Hydroxy-2-methylbenzenesulfonic acid ammonium is an impurity of Policresulen. Policresulen is a potent NS2B/NS3 protease inhibitor with an IC50 of 0.48 μg/mL. Policresulen effectively inhibits the replication of DENV2 virus in BHK-21 cells with an IC50 of 4.99 μg/mL. Policresulen acted as a competitive inhibitor of the protease, and slightly affected the protease stability[1].

[1]. Deng-wei Wu, et al. Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells. Acta Pharmacol Sin. 2015 Sep;36(9):1126-36.