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2'-Deoxypseudoisocytidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2'-Deoxypseudoisocytidine图片
CAS NO:65358-18-1
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
2'-Deoxypseudoisocytidine是一个核苷类似物。
Cas No.65358-18-1
Canonical SMILESO=C1C([C@@H]2O[C@H](CO)[C@@H](O)C2)=CN=C(N)N1
分子式C9H13N3O4
分子量227.22
溶解度DMSO : ≥ 106.5 mg/mL (468.71 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2'-Deoxypseudoisocytidine is a nucleoside analogue.

2'-Deoxypseudoisocytidine is a modified base which can be used as a allele-specific blocker probe to discriminate sequence variation between different alleles and quantitate rare (e.g., mutant) allelic variants, such as SNPs, or nucleotide (NT) insertions or deletions, in samples comprising abundant allelic variants with high specificity and selectivity[1]. 2'-Deoxypseudoisocytidine (2′d‐PIC) and its analogues are also used as novel base-pairing agents in oligonucleotides to investigate DNA and RNA structures and functions[2].

[1]. Caifu Chen, et al. Methods, Compositions, and Kits for Detecting Allelic Variants. US 20100285478 A1. [2]. Serpi M, et al. Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2'-Deoxypseudoisocytidine. ChemistryOpen. 2017 May 5;6(3):424-436.