Cyclotraxin B 是一种环状肽,是一种高效的选择性 TrkB 抑制剂,不会改变 BDNF 的结合。
Cas No. | 1203586-72-4 |
化学名 | (1E,3S,4Z,7Z,9S,10Z,12S,13Z,15S,16Z,18S,19Z,22Z,24R,29R,30Z,32S,37aS)-29-amino-15-(4-aminobutyl)-18-(2-carboxyethyl)-1,4,7,10,13,16,19,22,30-nonahydroxy-32-(2-hydroxy-2-iminoethyl)-9-(4-hydroxybenzyl)-12-((R)-1-hydroxyethyl)-3-(2-(methylthio)ethyl)-33-oxo |
Canonical SMILES | C[C@](O)([H])[C@@](/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)\[C@]1([H])CCCN12)([H])CCSC)([H])CC3=CC=C(O)C=C3)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/C/C(O)=N/[C@@](C(O)=O)([H])CSSC[C@@](N)([H])/C(O)=N/[C@@](C2=O)([H])CC(O)=N)([H])CCC(O)=O)([H])CCCCN |
分子式 | C48H73N13O17S3 |
分子量 | 1200.36 |
溶解度 | Soluble to 2 mg/ml in Water |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |