CAS NO: | 1086639-59-9 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Cas No. | 1086639-59-9 |
别名 | FAK Inhibitor 10 |
化学名 | 1-(2-hydroxyethyl)-1,3,5,7-tetraazaadamantan-1-ium bromide |
Canonical SMILES | OCC[N+]12CN3CN(C1)CN(C2)C3.[Br-] |
分子式 | C8H17N4OBr |
分子量 | 265.15 |
溶解度 | 10mg/mL in DMSO, 0.3mg/mL in DMF |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Focal adhesion kinases (FAKs) are non-receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over-expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397.[1] At 100 μM, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines.[1] Reference: |