CAS NO: | 1383920-14-6 |
包装: | 5mg |
市场价: | 3780元 |
An internal standard for the quantification of pristanic acid
Cas No. | 1383920-14-6 |
别名 | 降植烷酸 |
Canonical SMILES | OC(C(C([2H])([2H])[2H])CCCC(C)CCCC(C)CCCC(C)C)=O |
分子式 | C19H35D3O2 |
分子量 | 301.5 |
溶解度 | Ethanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Pristanic acid-d3 is intended for use as an internal standard for the quantification of pristanic acid by GC- or LC-MS. Pristanic acid is a saturated 19-carbon branched-chain fatty acid that has been found in human plasma.1 It can be formed from phytanic acid via α-oxidation or obtained from dietary sources.2 Pristanic acid activates peroxisome proliferator-activated receptor α (PPARα) in cell-based transactivation assays with a median EC50 value of 40 μM.1 Elevated levels of pristanic acid have been found in the plasma of patients with peroxisome biogenesis defects.2 |1. Zomer, A.W.M., van der Burg, B., Jansen, G.A., et al. Pristanic acid and phytanic acid: Naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor α. J. Lipid Res. 41(11), 1801-1807 (2000).|2. Verhoeven, N.M., and Jakobs, C. Human metabolism of phytanic acid and pristanic acid. Prog. Lipid Res. 40(6), 453-466 (2001). |