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Pristanic Acid-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pristanic Acid-d3图片
CAS NO:1383920-14-6
包装:5mg
市场价:3780元

产品介绍

An internal standard for the quantification of pristanic acid

Cas No.1383920-14-6
别名降植烷酸
Canonical SMILESOC(C(C([2H])([2H])[2H])CCCC(C)CCCC(C)CCCC(C)C)=O
分子式C19H35D3O2
分子量301.5
溶解度Ethanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pristanic acid-d3 is intended for use as an internal standard for the quantification of pristanic acid by GC- or LC-MS. Pristanic acid is a saturated 19-carbon branched-chain fatty acid that has been found in human plasma.1 It can be formed from phytanic acid via α-oxidation or obtained from dietary sources.2 Pristanic acid activates peroxisome proliferator-activated receptor α (PPARα) in cell-based transactivation assays with a median EC50 value of 40 μM.1 Elevated levels of pristanic acid have been found in the plasma of patients with peroxisome biogenesis defects.2

|1. Zomer, A.W.M., van der Burg, B., Jansen, G.A., et al. Pristanic acid and phytanic acid: Naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor α. J. Lipid Res. 41(11), 1801-1807 (2000).|2. Verhoeven, N.M., and Jakobs, C. Human metabolism of phytanic acid and pristanic acid. Prog. Lipid Res. 40(6), 453-466 (2001).