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Palmatine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Palmatine图片
CAS NO:3486-67-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
20mg电议

产品介绍
Palmatine 是一种口服活性的不可逆 IDO-1 抑制剂。Palmatine 可以减轻结肠损伤,预防肠道菌群失调和调节色氨酸分解代谢,从而改善DSS诱发的结肠炎。Palmatine 具有治疗结肠炎的潜力。
Cas No.3486-67-7
别名黄藤素
Canonical SMILESCOC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(OC)C=C4CC3)C=C2C=C1
分子式C21H22NO4+
分子量352.4
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor. Palmatine can ameliorate DSS-induced colitis by mitigating colonic injury, preventing gut microbiota dysbiosis, and regulating tryptophan catabolism. Palmatine has the potential for colitis treatment[1].

[1]. Zhang XJ, et al. Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota.Pharmacol Res. 2018 Nov;137:34-46.