CAS NO: | 1962931-71-0 |
包装: | 10mg |
市场价: | 5027元 |
Cas No. | 1962931-71-0 |
Canonical SMILES | BrC1=C(OC2=C(F)C=C(/C=C3\SC(NCCC4=CC=CC=N4)=NC3=O)C=C2)C=CC(C#N)=C1 |
分子式 | C24H16BrFN4O2S |
分子量 | 523.38 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | DGAT2 inhibitor (IC50 = 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2. Qi et al (2012) The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J.Lipid Res. 53 1106 PMID:22493088 |Irshad et al (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. J.Lipid Res. 58 15 PMID:27836993 |