| CAS NO: | 219315-22-7 |
| 包装: | 25mg |
| 市场价: | 810元 |
| Cas No. | 219315-22-7 |
| Canonical SMILES | C\C(=N/NC1=C(Cl)C=C(Cl)C=C1Cl)C1=C(O)C=CC(Cl)=C1 |
| 分子式 | C14H10Cl4N2O |
| 分子量 | 364.05 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mitochondrial fusion promoter. Protects cells from mitochondrial fragmentation-associated cell death. Induces mitochondrial fusion in effector T cells imposing a memory T cell morphology. Improves cellular respiration and potentiates glucose-stimulated insulin-secretion in cholesterol-exposed pancreatic β cells. Asalla et al (2016) Restoring mitochondrial function: a small molecule-mediated approach to enhance glucose stimulated insulin secretion in cholesterol accumulated pancreatic beta cells. Sci.Rep. 10 27513 PMID:27282931 |Wang et al (2012) A small molecule promotes mitochondrial fusion in mammalian cells. Angew.Chem.Int.Ed.Engl. 51 9302 PMID:22907892 |Buck et al (2016) Mitochondrial dynamics controls T cell fate through metabolic programming. Cell 166 63 PMID:27293185 |
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