CAS NO: | 559-74-0 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 559-74-0 |
别名 | 软木三萜酮 |
Canonical SMILES | C[C@@]12[C@]([C@@]3([H])[C@](C)(CCC(C)(C)C3)CC1)(CC[C@]4(C)[C@]2([H])CC[C@@]([C@H]5C)(C)[C@@]4([H])CCC5=O)C |
分子式 | C30H50O |
分子量 | 426.72 |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively[1]. [1]. Wei J, et al. In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes. Pharm Biol. 2018 Dec;56(1):363-367. |