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Ilexsaponin B2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ilexsaponin B2图片
CAS NO:108906-69-0
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
IlexsaponinB2是从IlexpubescensHook.etArn.中分离出来的一种皂苷,也是一种有效的磷酸二酯酶5(PDE5)和PDEI抑制剂,IC50值分别为48.8μM和477.5μM。
Cas No.108906-69-0
别名青皂苷B2;毛冬青皂苷B2
Canonical SMILESOC([C@]12[C@]([C@](O)([C@@H](C)CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@@H](O[C@@]5([H])[C@@H]([C@H]([C@H](O)CO5)O)O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O6)O)O[C@@]7([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O7)O)O)CC4)C)([H])CC8)C)([H])[C@]8(C)[C@]3(C)CC1)=O
分子式C47H76O17
分子量913.1
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively[1].

[1]. Zichen Liu, et al. Rapid Screening of Potential Phosphodiesterase Inhibitors From the Roots of Ilex pubescens Hook. Et Arn. Using a Combination of Ultrafiltration and LC-MS. Evid Based Complement Alternat Med. 2017;2017:2749643.