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1-Ethynylpyrene
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Ethynylpyrene图片
CAS NO:34993-56-1
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品介绍
1-Ethynylpyrene是细胞色素P4501A1,1A2和2B1的抑制剂,IC50分别为0.18,0.32和0.04μM。
Cas No.34993-56-1
别名1-乙炔基芘
Canonical SMILESC#CC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1
分子式C18H10
分子量226.27
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].

1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively[1].

[1]. Naijue Zhu, et al. Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450. J Chem Crystallogr. 2010 Apr 1;40(4):343-352.