Aurora Kinase Inhibitor III 是一种强效选择性 Aurora A 激酶抑制剂，IC50 为 42 nM，弱抑制 EGFR，IC50 >10 μM。
| Cas No. | 879127-16-9 |
| 化学名 | N-(3-((4-((3-(trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide |
| Canonical SMILES | O=C(NC1=CC=CC(NC2=NC=CC(NC3=CC=CC(C(F)(F)F)=C3)=N2)=C1)C4CC4 |
| 分子式 | C21H18F3N5O |
| 分子量 | 413.40 |
| 溶解度 | ≥ 18.32 mg/mL in DMSO with ultrasonic, ≥ 2.62 mg/mL in EtOH with ultrasonic and warming |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Aurora Kinase Inhibitor III |
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