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Flavokawain C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Flavokawain C图片
CAS NO:37308-75-1
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Flavokawain C 是存在卡瓦胡椒根中的天然查尔酮。Flavokawain C 对多种人类癌症细胞系产生细胞毒性,对 HCT 116 细胞作用的 IC50 值为 12.75 μM。
Cas No.37308-75-1
别名卡瓦胡椒素C
Canonical SMILESO=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(O)C=C2
分子式C17H16O5
分子量300.31
溶解度DMSO: 12.5 mg/mL (41.62 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells[1].

[1]. Phang CW, et al. Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells. PLoS One. 2016 Feb 9;11(2):e0148775.