| CAS NO: | 2271081-58-2 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 2271081-58-2 |
| Canonical SMILES | COC1=CC=C(CN2N=NC(C(N/N=C3C(NC4=C\3C=CC=C4C)=O)=O)=C2)C=C1 |
| 分子式 | C20H18N6O3 |
| 分子量 | 390.4 |
| 溶解度 | DMSO: 5 mg/mL (12.81 mM; ultrasonic and adjust pH to 2 with HCl) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1]. IC50: 1.54 μM (MARK4)[1]. [1]. Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163:840-852. |
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