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Sulazepam
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sulazepam图片
CAS NO:2898-13-7
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Sulazepam 是一种苯二氮卓类药物,是一种选择性卵巢癌 G 蛋白偶联受体 (OGR1) 激动剂。Sulazepam 具有抗惊厥作用,也有用于气道高反应性 (AHR) 研究的潜力。
Cas No.2898-13-7
别名硫西泮
分子式C16H13ClN2S
分子量300.81
溶解度DMSO : 50 mg/mL (166.22 mM; ultrasonic and warming and heat to 60°C)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research[1][2].

Sulazepam (3.2 mg/kg in 25 µL via intranasal route ∼30 min before HDM challenge; 5 days a week for three consecutive weeks) inhibits the development of airway hyperresponsiveness (AHR) in Male and female wild-type C57BL/6 mice (8-10 wk old), but not in age-matched OGR1KO mice (C57BL/6 background) with house dust mite (HDM) allergen (25 μg; intranasally)[1].