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Benzoylmesaconitine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Benzoylmesaconitine图片
CAS NO:63238-67-5
包装:20mg
市场价:1722元

产品介绍
苯甲酰美沙乌碱是乌头汤中含量最多的成分,因其对类风湿性关节炎的治疗作用而在我国被广泛使用。
Cas No.63238-67-5
别名苯甲酰新乌头原碱; Mesaconine 14-benzoate
化学名(3R,4R,7S,7aR,8R,9S,10S,11S,11aR,13R,14S)-4,9,11,11a-tetrahydroxy-6,10,13-trimethoxy-3-(methoxymethyl)-1-methyltetradecahydro-1H-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocin-8-yl benzoate
分子式C31H43NO10
分子量589.67
溶解度≥ 59mg/mL in DMSO
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Benzoylmesaconine is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis.

References:
[1]. Dai PM, et al. Pharmacokinetic comparisons of benzoylmesaconine in rats using ultra-performance liquid chromatography-tandem mass spectrometry after administration of pure benzoylmesaconine and Wutou decoction. Molecules. 2014 Oct 17;19(10):16757-69.
[2]. Ye L, et al. Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5. Evid Based Complement Alternat Med. 2013;2013:941093.