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4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene图片
CAS NO:160854-54-6
包装:1g
市场价:9533元

产品介绍
4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene 是一种不可降解 (non-cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
Cas No.160854-54-6
分子式C17H14N2O4S2
分子量374.43
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.