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8-bromo-Cyclic ADP-Ribose(sodium salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
8-bromo-Cyclic ADP-Ribose(sodium salt)图片
包装:1mg
市场价:5730元

产品介绍
Canonical SMILESBrC1=NC2=C(N1[C@]3([H])O[C@@]4([H])[C@@H](O)[C@H]3O)N=CN([C@@]5([H])[C@H](O)[C@H](O)[C@](COP(OP(OC4)(O)=O)(O)=O)([H])O5)C2=N.[Na+].[Na+]
分子式C15H20BrN5O13P2•2Na
分子量666.2
溶解度Water: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 µM. It is commonly used to investigate intracellular signaling through cADP-ribose in isolated cells and tissues.