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Brevetoxin B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Brevetoxin B图片
CAS NO:79580-28-2
包装:100μg
市场价:3251元

产品介绍
Brevetoxin B (Brevetoxin-2; PbTx-2) 是一种由卡列尼亚属和其他甲藻产生的聚酮类神经毒素。
Cas No.79580-28-2
别名短裸甲藻毒素2,Brevetoxin-2; PbTx-2
Canonical SMILESCC1=CC(OC2C1OC3(C)C(OC4C(OC5C(OC(CC(OC6(C)C(OC7C(OC(CC(OC(CC(C=O)=C)CC8O)C8(C)O9)C9C7)/C=C\C6)C%10)C%10(C)O%11)C%11(C)CC5)C(C)C4)C3)C2)=O
分子式C50H70O14
分子量895.1
溶解度Ethyl Acetate: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.