CAS NO: | 192140-58-2 |
包装: | 50μg |
市场价: | 741元 |
Cas No. | 192140-58-2 |
别名 | 钙离子荧光探针FURA-FF,五钾盐 |
化学名 | 2-[6-[bis(carboxymethyl)amino]-5-[2-[6-[bis(carboxymethyl)amino]-2,3-difluorophenoxy]ethoxy]-2-benzofuranyl]-5-oxazolecarboxylic acid, pentapotassium salt |
Canonical SMILES | [O-]C(CN(C1=CC2=C(C=C(C3=NC=C(C([O-])=O)O3)O2)C=C1OCCOC(C(F)=C(F)C=C4)=C4N(CC([O-])=O)CC([O-])=O)CC([O-])=O)=O.[K+].[K+].[K+].[K+].[K+] |
分子式 | C28H18F2N3O14o 5K |
分子量 | 853.9 |
溶解度 | Soluble in water |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation.[1] Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively).[1],[2]However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presence of a high calcium concentration.[3] Low affinity calcium dyes, including fura-FF, are preferred for studying compartments with high concentrations of calcium, such as mitochondria, or in cell systems that have relatively low calcium buffering capacities, such as neuronal dendrites and spines.[4],[5[,[6] Refererence: |