CAS NO: | 852146-73-7 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 852146-73-7 |
Canonical SMILES | FC1=CC=C(C)C(C2=CC=C(C(NC(N)=N)=O)O2)=C1 |
分子式 | C13H12FN3O2 |
分子量 | 261.3 |
溶解度 | DMSO: ~ 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). It restores cardiac contractile function ex vivo in an isolated ischemic rat heart model when used at a concentration of 10 μM. KR-32568 (0.3 mg/kg) reduces myocardial infarct size in a rat model of ischemia and reperfusion injury. |