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KR-32568
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KR-32568图片
CAS NO:852146-73-7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Cas No.852146-73-7
Canonical SMILESFC1=CC=C(C)C(C2=CC=C(C(NC(N)=N)=O)O2)=C1
分子式C13H12FN3O2
分子量261.3
溶解度DMSO: ~ 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). It restores cardiac contractile function ex vivo in an isolated ischemic rat heart model when used at a concentration of 10 μM. KR-32568 (0.3 mg/kg) reduces myocardial infarct size in a rat model of ischemia and reperfusion injury.