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Alclofenac
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Alclofenac图片
CAS NO:22131-79-9
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品介绍
An NSAID
Cas No.22131-79-9
别名烯氯苯乙酸
Canonical SMILESOC(CC1=CC(Cl)=C(OCC=C)C=C1)=O
分子式C11H11ClO3
分子量226.7
溶解度Chloroform: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Alclofenac is a non-steroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and anti-pyretic properties.1,2,3It inhibits contractions induced by serotonin (5-HT) in isolated guinea pig ileum by 28% when used at a concentration of 200 μg/ml.4Alclofenac (480 mg/kg per day) decreases implant neutrophil and macrophage infiltration in a rat model of irritant-induced inflammation induced by implantation of heat-killedM. tuberculosis-impregnated polyurethane cubes.5

1.Delbeke, F.T., Landuyt, J., and Debackere, M.Disposition of human drug preparations in the horse. III. Orally administered alclofenacJ. Vet. Pharmacol. Ther.17(5)353-358(1994) 2.Staquet, M., Luyckx, A., and Van Cauwenberge, H.A double-blind comparison of alclofenac, pentazocine, and codeine with placebo control in pathologic painJ. Clin. Pharmacol. New Drugs11(6)450-455(1971) 3.Berry, H., Fernandes, L., Ford-Hutchinson, A.W., et al.Alclofenac and ?-penicillamine. Comparative trial in rheumatoid arthritisAnn. Rheum. Dis.37(1)93-97(1978) 4.Famaey, J.P., Fontaine, J., Seaman, I., et al.A possible role of prostaglandins in guinea-pig isolated ileum contractions to serotoninProstaglandins14(1)119-124(1977) 5.Woodland, J., Vernon-Roberts, B., Swettenham, K.V., et al.Comparison of the effects of alclofenac, flurbiprofen, and prednisolone on acute inflammatory response in the ratAnn. Rheum. Dis.36(2)160-165(1977)