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Pipamperone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pipamperone图片
CAS NO:1893-33-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Pipamperone (Floropipamide; McN-JR 3345; R 3345) 是 5-HT2A 受体 (pKi=8.2) 和 D4 受体 (pKi=8.0) 的高亲和力拮抗剂。Pipamperone (Floropipamide; McN-JR 3345; R 3345) 是 D2 受体 (pKi=6.7) 的低亲和力拮抗剂。
Cas No.1893-33-0
别名酰胺哌啶酮,Floropipamide; McN-JR 3345; R 3345
Canonical SMILESO=C(C1(N2CCCCC2)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC1)N
分子式C21H30FN3O2
分子量375.48
溶解度0.1 M HCL: 25 mg/mL (66.58 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7)[1]. 5-HT2A Receptor|8.2 (pKi)|5-HT2C Receptor|6.9 (pKi)|5-HT1 Receptor|5.7 (pKi)|D4 receptor|8.0 (pKi)|D2 receptor|6.7 (pKi)|α1 receptor|7.2 (pKi)

[1]. Erik Buntinx, MD, et al. Selective Serotonergic Properties of Low-Dose Pipamperone May Enhance Antidepressant Effect: Preclinical Evidence.