Cas No. | 158018-53-2 |
别名 | 4-差向四环素盐酸盐 |
化学名 | (4R,4aS,12aS)- 7-chloro-4-(dimethylamino)-1,4,4a,5,12a,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide, monohydrochloride |
Canonical SMILES | O=C([C@@](C(C(C(N)=O)=C(O)[C@@H]1N(C)C)=O)(O)[C@@]1([H])C2)C3=C2C(C)=C4C(C(O)=CC=C4Cl)=C3O.Cl |
分子式 | C22H21ClN2O7.HCl |
分子量 | 497.3 |
溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 4-Epianhydrochlortetracycline is a derivative of tetracycline . It inhibits matrix metalloproteinase-9 (MMP-9) activity in a dose-dependent manner in an assay for collagen degradation. 4-Epianhydrochlortetracycline also completely inhibits neutrophil-derived MMP-9 degradation of denatured collagen at a concentration of 500 μg/ml. Unlike tetracycline, 4-epianhydrochlortetracycline lacks antibiotic activity. |