您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Aloisine RP106
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Aloisine RP106
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Aloisine RP106图片
CAS NO:496864-15-4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
Aloisine RP106 (compound 38) 是 Cdk1/cyclin B、Cdk5/p25 和 GSK3 的有效抑制剂,IC50 分别为 0.70μM、1.5μM、0.92 μM。
Cas No.496864-15-4
别名7-丁基-6-(4-甲氧基苯基)-5H-吡咯并[2,3-B]吡嗪
化学名7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
Canonical SMILESCOC(C=C1)=CC=C1C2=C(CCCC)C3=NC=CN=C3N2
分子式C17H19N3O
分子量281.4
溶解度DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 12 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述 Aloisine is an inhibitor of Cdk1/cyclin B, Cdk5/p25, and GSK3 (IC50s = 0.70, 1.5, and 0.92 uM, respectively). It is a derivative of the aloisines A and B, which competitively inhibit ATP binding to the catalytic subunit of CDKs and GSKs.