Illudin M 是一种细胞毒性真菌倍半萜,可从 Omphalotus olearius 蘑菇的培养基中分离出来。 Illudin M 可以烷基化 DNA。 Illudin M 具有抗肿瘤活性。
Cas No. | 1146-04-9 |
别名 | 隐陡头菌素M |
Canonical SMILES | O=C1C2=CC(C)(C)[C@H](O)C2=C(C)C3(CC3)[C@]1(O)C |
分子式 | C15H20O3 |
分子量 | 248.3 |
溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies. |