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CAY10767
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10767图片
CAS NO:2376590-40-6
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议

产品介绍
A PPARα agonist
Cas No.2376590-40-6
Canonical SMILESOC(C1=CC=CC(NCC2=CC(C)=C(OCC3=CC=C(F)C=C3)C=C2)=C1)=O
分子式C22H20FNO3
分子量365.4
溶解度DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:2): 0.3mg/mL,DMSO: 5mg/mL,Ethanol: 12mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CAY10767 is an agonist of peroxisome proliferator-activated receptor α (PPARα; EC50= 37 nM in a reporter assay).1It is greater than 2,700-fold selective for PPARα over PPARγ or PPARδ.

1.Dou, X., Nath, D., Shin, H., et al.Evolution of a 4?benzyloxy-benzylamino chemotype to provide efficacious, potent, and isoform selective PPARα agonists as leads for retinal disordersJ. Med. Chem.63(6)2854-2876(2020)