| CAS NO: | 477-29-2 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Cas No. | 477-29-2 |
| 别名 | 秋水仙碱苷 |
| Canonical SMILES | O[C@H]([C@H]1O)[C@H](O)[C@@H](CO)O[C@H]1OC2=CC3=C(C(C([C@@H](NC(C)=O)CC3)=C4)=CC=C(OC)C4=O)C(OC)=C2OC |
| 分子式 | C27H33NO11 |
| 分子量 | 547.6 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Colchicoside is a glycoside form of 3-demethylcolchicine that has been found inG. superba.1Unlike cholchicine and 3-demethylcolchicine, colchicoside does not displace [3H]-colchicine from rat brain tubulinin vitrowhen used at a concentration of 25 μM.2Colchicoside (1 and 10 μM) increases levels of the cytochrome P450 (CYP) isoforms CYP2C9 and CYP2E1 in primary human hepatocytes.3 1.Capistrano, I.R., Vangestel, C., Vanpachtenbeke, H., et al.Coadministration of a Gloriosa superba extract improves the in vivo antitumoural activity of gemcitabine in a murine pancreatic tumour modePhytomedicine23(12)1434-1440(2016) 2.Sugio, K., Maruyama, M., Tsurufuji, S., et al.Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congenersLife Sci.40(1)35-39(1987) 3.DvorÁk, Z., UlrichovÁ, J., ModrianskÝ, M., et al.Effect of colchicine and its derivatives on the expression of selected isoforms of cytochrome P450 in primary cultures of human hepatocytesActa Univ. Palacki. Olomuc. Fac. Med.14347-50(2000) |
m.cnreagent.com