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Eltenac
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eltenac图片
CAS NO:72895-88-6
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议

产品介绍
Eltenac 是一种非甾体抗炎药 (NSAID),是一种 COX 抑制剂。
Cas No.72895-88-6
别名依尔替酸
Canonical SMILESClC1=C(NC2=CSC=C2CC(O)=O)C(Cl)=CC=C1
分子式C12H9Cl2NO2S
分子量302.2
溶解度DMF: soluble,DMSO: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Eltenac is a non-selective COX inhibitor (IC50= 0.03 µM for both COX-1 and COX-2 in isolated human whole blood) and a non-steroidal anti-inflammatory drug (NSAID).1In vivo, eltenac (1 mg/kg) reduces lameness in horses with tendinitis, pododermatitis, navicular disease, non-infectious arthritis, degenerative joint disease, phalanx fracture, and osteochondrosis.2It also reduces castration-induced edema in horses. Formulations containing eltenac have been used in the treatment of postoperative swelling in horses.

1.Klein, T., Dullweber, F., Brehm, C., et al.Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivoBiochem. Pharmacol.76(6)717-725(2008) 2.PrÜgner, W., Huber, R., and LÜhmann, R.Eltenac, a new anti-inflammatory and analgesic drug for horses: clinical aspectsJ. Vet. Pharmacol. Ther.14(2)193-199(1991)