| Cas No. | 1821908-49-9 |
| 化学名 | 2S-amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]-propanamide, monohydrochloride |
| Canonical SMILES | CC1=CC(C)=CC(OC2=CC=C(CNC([C@@H](N)C)=O)C=C2C)=C1.Cl |
| 分子式 | C19H24N2O2.HCl |
| 分子量 | 348.9 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:10): 0.1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SGC2085 is an inhibitor of protein arginine methyltransferase 4 (PRMT4/CARM1; IC50 = 50 nM). It is selective for PRMT4/CARM1 over PRMT8 at concentrations up to 50 uM and PRMT1, PRMT3, PRMT5, and PRMT7 up to 100 uM. SGC2085 also weakly inhibits PRMT6 (IC50 = 5.2 uM). It has no activity in HEK293 cells at concentrations up to 10 uM. |
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