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SIRT5 inhibitor
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
SIRT5 inhibitor图片
CAS NO:2166487-21-2
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
SIRT5 inhibitor 是一种有效的 Human Sirtuin 5 deacylase 抑制剂，IC50 为 0.11 μM.
Cas No.2166487-21-2
Canonical SMILESO=S(N[C@@H](CCCCNC(NCCC(O)=O)=S)C(N[C@H](C(NC1CCC1)=O)CC2=CNC3=CC=CC=C23)=O)(C4=CC(F)=CC=C4)=O
分子式C31H39FN6O6S2
分子量674.81
溶解度DMSO : 125 mg/mL (185.24 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.

SIRT5 inhibitor (compound 49) is a very potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM, >100-fold from compound 1[1].

[1]. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841.