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Harzianum A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Harzianum A图片
CAS NO:156250-74-7
包装:10mg
市场价:12081元

产品介绍
Harzianum A 是从土壤传播的真菌 Trichoderma harzianum 中分离出来的单端孢菌素。
Cas No.156250-74-7
Canonical SMILESCC1=C[C@]2([H])[C@](C3(C)C4(OC4)[C@](C[C@H]3OC(/C=C\C=C\C=C\C(O)=O)=O)([H])O2)(C)CC1
分子式C23H28O6
分子量400.5
溶解度DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Harzianum A is a trichothecene fungal metabolite originally isolated from T. harzianum.1 It is cytotoxic to HeLa, MCF-7, and HT-1080 cells (IC50s = 5.07, 10.13, and 0.65 μg/ml, respectively) and exhibits antifungal activity against C. albicans and S. cerevisiae when used at a concentration of 100 μg/ml.1,2

References
1. Corley, D.G., Miller-Wideman, M., and Durley, R.C. Isolation and structure of harzianum A: A new trichothecene from Trichoderma harzianum. J. Nat. Prod. 57(3), 422-425 (1994).
2. Lee, H.B., Kim, Y., Jin, H.Z., et al. A new Hypocrea strain producing harzianum A cytotoxic to tumour cell lines. Lett. Appl. Microbiol. 40(6), 497-503 (2005).