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Carubicin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Carubicin图片
CAS NO:50935-04-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Carubicin (Carminomycin) 是一种微生物衍生的化合物。
Cas No.50935-04-1
别名洋红霉素,Carminomycin; Carminomicin I
Canonical SMILESOC1=C(C2=O)C(C(C(C2=C3O)=C(O)C4=C3[C@@H](O[C@]5([H])O[C@@H](C)[C@@H](O)[C@@H](N)C5)C[C@@](C(C)=O)(O)C4)=O)=CC=C1
分子式C26H27NO10
分子量513.5
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carubicin is an anthracycline originally isolated from A. carminata that has anticancer activity.1,2 It is cytotoxic to MCF-7 and K562 cells (IC50s = 90 and 60 nM, respectively), as well as P-glycoprotein-expressing MCF-7/DOX and K562i/S9 cells (IC50s = 90 and 60 nM, respectively).1

|1. Tevyashova, A.N., Shtil, A.A., Olsufyeva, E.N., et al. Carminomycin, 14-hydroxycarminomycin and its novel carbohydrate derivatives potently kill human tumor cells and their multidrug resistant variants. J. Antibiot. (Tokyo) 57(2), 143-150 (2004).|2. Gause, G.F., Brazhnikova, M.G., and Shorin, V.A. A new antitumor antibiotic, carminomycin (NSC-180024). Cancer Chemother. Rep. 58(2), 255-256 (1974).