| CAS NO: | 50935-04-1 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 50935-04-1 |
| 别名 | 洋红霉素,Carminomycin; Carminomicin I |
| Canonical SMILES | OC1=C(C2=O)C(C(C(C2=C3O)=C(O)C4=C3[C@@H](O[C@]5([H])O[C@@H](C)[C@@H](O)[C@@H](N)C5)C[C@@](C(C)=O)(O)C4)=O)=CC=C1 |
| 分子式 | C26H27NO10 |
| 分子量 | 513.5 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Carubicin is an anthracycline originally isolated from A. carminata that has anticancer activity.1,2 It is cytotoxic to MCF-7 and K562 cells (IC50s = 90 and 60 nM, respectively), as well as P-glycoprotein-expressing MCF-7/DOX and K562i/S9 cells (IC50s = 90 and 60 nM, respectively).1 |1. Tevyashova, A.N., Shtil, A.A., Olsufyeva, E.N., et al. Carminomycin, 14-hydroxycarminomycin and its novel carbohydrate derivatives potently kill human tumor cells and their multidrug resistant variants. J. Antibiot. (Tokyo) 57(2), 143-150 (2004).|2. Gause, G.F., Brazhnikova, M.G., and Shorin, V.A. A new antitumor antibiotic, carminomycin (NSC-180024). Cancer Chemother. Rep. 58(2), 255-256 (1974). |
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