| CAS NO: | 1334532-26-1 |
| 包装 | 价格(元) |
| 500 μg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 1334532-26-1 |
| 别名 | 十六烷酰基-L-肉碱-d3 （盐酸盐） |
| Canonical SMILES | OC(C[C@H](C[N+](C([2H])([2H])[2H])(C)C)OC(CCCCCCCCCCCCCCC)=O)=O.[Cl-] |
| 分子式 | C23H43D3NO4.Cl |
| 分子量 | 439.1 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 20 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Palmitoyl-L-carnitine-d3is intended for use as an internal standard for the quantification of palmitoyl-L-carnitine by GC- or LC-MS. Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine .1In cells, palmitoyl-L-carnitine is transported into mitochondriaviacarnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production.2It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 µM.3In vivo, palmitoyl-L-carnitine increases intestinal absorption of the antibiotic cefoxitin in rat intestine.4 1.Bezaire, V., Bruce, C.R., Heigenhauser, G.J.F., et al.Identification of fatty acid translocase on human skeletal muscle mitochondrial membranes: Essential role in fatty acid oxidationAm. J. Physiol. Endocrinol. Metab.290(3)E509-E515(2006) 2.El-Hayek, R., Valdivia, C., Valdivia, H.H., et al.Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by palmitoyl carnitineBiophys. J.65(2)779-789(1993) 3.Bell, F.P.Carnitine esters: Novel inhibitors of plasma lecithin: Cholesterol acyltransferase in experimental animals but not in man (Homo sapiens)Int. J. Biochem.15(2)133-136(1983) 4.Sutton, S.C., LeCluyse, E.L., Cammack, L., et al.Enhanced bioavailability of cefoxitin using palmitoyl L-carnitine. I. Enhancer activity in different intestinal regionsPharm. Res.9(2)191-194(1992) |
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