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SHMT-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SHMT-IN-1图片
CAS NO:1508286-18-7
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议

产品介绍
SHMT-IN-1 (compound (±)-46) 是有效的血浆丝氨酸羟甲基转移酶 (SHMT) 抑制剂。SHMT-IN-1 具有抗肿瘤活性。
Cas No.1508286-18-7
分子式C18H16Cl2N4O
分子量375.25
溶解度DMSO : 250 mg/mL (666.22 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT). SHMT-IN-1 has antitumor activity[1].

[1]. Witschel MC, et al. Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. J Med Chem. 2015 Apr 9;58(7):3117-30.