| Cas No. | 897613-29-5 |
| Canonical SMILES | CC(NC1=CC=CC(NC(C(NCCC2=C(C)N=C(C3=CC=C(C)C=C3)S2)=O)=O)=C1)=O |
| 分子式 | C23H24N4O3S |
| 分子量 | 436.5 |
| 溶解度 | DMF: 3 mg/ml,DMF:PBS(pH7.2) (1:2): 0.33 mg/ml,DMSO: 2 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation. It diminishes endogenous oxidative damage in primary astrocytes, reduces stress-induced signaling in a cardiomyocyte cell model, and protects against ischemia-reperfusion injury in perfused mouse heart. |
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