RUVBL1/2 ATPase-IN-1

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	423128-55-6
包装:	5mg
市场价:	10350元

产品介绍

RUVBL1/2 ATPase-IN-1 (compound 18) 是一种有效且选择性的 RUVBL1/2 ATPase 抑制剂，IC50 值为 6.0 和 7.7 μM，分别。RUVBL1 和 RUVBL2 是高度保守的 AAA ATP 酶 (与各种细胞活动相关的 ATP 酶)，与癌症的进展高度相关。RUVBL1/2 ATPase-IN-1 具有研究癌症疾病的潜力。

Cas No.	423128-55-6
分子式	C28H28F3N5O
分子量	507.55
溶解度	DMSO : 10 mg/mL (19.70 mM; ultrasonic and warming and heat to 60℃)
储存条件	4°C, protect from light
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	RUVBL1/2 ATPase-IN-1 (compound 18) is a potent and selective inhibitor of RUVBL1/2 ATPase with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1 and RUVBL2 are highly conserved AAA ATPases (ATPases Associated with various cellular Activities) and highly relevant to the progression of cancer. RUVBL1/2 ATPase-IN-1 has the potential for the research of cancer diseases[1]. [1]. Zhang G, et al. Discovery of small-molecule inhibitors of RUVBL1/2 ATPase. Bioorg Med Chem. 2022;62:116726.