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AMG2850
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AMG2850图片
CAS NO:1470018-52-0
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
AMG2850 是一个有效的、有口服活性的TRPM8 的选择性拮抗剂。
Cas No.1470018-52-0
Canonical SMILESO=C(N1CCC2=C(N=CC=C2)[C@H]1C3=CC=C(C(F)(F)F)C=C3)N[C@@H](C)C(F)(F)F
分子式C19H17F6N3O
分子量417.35
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist[1]. TRPM8[1].

[1]. Lehto SG, et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):465-76.