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Cav 2,2 blocker 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cav 2,2 blocker 1图片
CAS NO:1567335-29-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
Cav 2.2 blocker 1 (compound 9) 是一种 N 型钙离子通道 (Cav 2.2) 的阻断剂,可用于治疗疼痛,IC50 值为 1 nM。
Cas No.1567335-29-8
Canonical SMILESCOC(C=CC=C1)=C1N2C(C3=CC=C(Cl)C=C3)=CC(C4CC(C)(C)OC(C)(C)C4)=N2
分子式C25H29ClN2O2
分子量424.96
溶解度DMSO: 20.83 mg/mL (49.02 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1]. IC50: 1 nM (Cav 2.2)[1].

[1]. Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783.