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Coniferyl ferulate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Coniferyl ferulate图片
CAS NO:63644-62-2
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Coniferyl ferulate,一种从 Angelicae sinensis 中分离的谷胱甘肽 S-转移酶 (GST) 的强抑制剂,可逆转多药耐药性并下调 P-糖蛋白。Coniferyl ferulate 强抑制人胎盘型谷胱甘肽 S-转移酶,IC50 为 0.3?μM。
Cas No.63644-62-2
别名阿魏酸松柏酯
Canonical SMILESO=C(OC/C=C/C1=CC=C(O)C(OC)=C1)/C=C/C2=CC=C(O)C(OC)=C2
分子式C20H20O6
分子量356.37
溶解度DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 3 mg/ml
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1]. Glutathione S-transferase[1]P-glycoprotein[1]

[1]. Chen C, et al. Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein. Evid Based Complement Alternat Med. 2013;2013:639083.