Gallopamil

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Gallopamil

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

16662-47-8

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
50mg	电议
100mg	电议
200mg	电议

产品介绍

Gallopamil (Methoxyverapamil) 是一种维拉帕米的甲氧基衍生物 (methoxy derivative of verapamil)，也是一种苯基烷基胺钙 (phenylalkylamine calcium)拮抗剂。Gallopamil 可以作用于血管系统，心脏及其淋巴结构。Gallopamil 以浓度依赖性方式抑制酸分泌，IC50 为 10.9 μM.

Cas No.	16662-47-8
别名	戈洛帕米,Methoxyverapamil
Canonical SMILES	COC1=C(OC)C(OC)=CC(C(CCCN(C)CCC2=CC(OC)=C(OC)C=C2)(C#N)C(C)C)=C1
分子式	C₂₈H₄₀N₂O₅
分子量	484.63
溶解度	DMSO: 100 mg/mL (206.34 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. Gallopamil acts on the vascular system and the heart and nodal structure[1]. Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM[2]. Ca2+ [1]. Brogden RN, et al. Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease. Drugs. 1994 Jan;47(1):93-115. [2]. Sewing KF, et al. Calcium channel antagonists verapamil and gallopamil are powerful inhibitors of acid secretion in isolated and enriched guinea pig parietal cells. Pharmacology. 1983;27(1):9-14.