CAS NO: | 1235403-62-9 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
25mg | 电议 |
100mg | 电议 |
Cas No. | 1235403-62-9 |
Canonical SMILES | O=S(C1=CC(Cl)=C(OC2=CC=C(Cl)C=C2C3=CNN=C3N)C=C1F)(NC4=CSC=N4)=O |
分子式 | C18H12Cl2FN5O3S2 |
分子量 | 500.35 |
溶解度 | DMSO: ≥ 34 mg/mL (67.95 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | PF 05089771 is a Nav1.7 channel blocker extracted from patent WO/2010/079443 A1, compound example 788, has an IC50 of 8.6 nM. [1]. Norinder U, et al. QSAR investigation of NaV1.7 active compounds using the SVM/Signature approach and the Bioclipse Modeling platform. Bioorg Med Chem Lett. 2013 Jan 1;23(1):261-3. [2]. BEAUDOIN, et al. SULFONAMIDE DERIVATIVES. Patent WO/2010/079443 A1. |