| CAS NO: | 167105-81-9 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| Cas No. | 167105-81-9 |
| 别名 | 酮咯酸钙盐,RS37619 hemicalcium |
| Canonical SMILES | O=C(C1=CC=C2N1CCC2C([O-])=O)C3=CC=CC=C3.O=C(C4=CC=C5N4CCC5C([O-])=O)C6=CC=CC=C6.[Ca+2] |
| 分子式 | C15H12NO3.1/2Ca |
| 分子量 | 274.3 |
| 溶解度 | DMSO: 1 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) and a non-selective COX inhibitor (IC50= 20 nM for both COX-1 and COX-2).1It prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases prostaglandin E2(PGE2) levels in paw tissue in a mouse model of carrageenan-induced inflammation when administered at a dose of 30 mg/kg. Ketorolac is a racemic mixture containing the active (S)-ketorolac and inactive (R)-ketorolac enantiomers. Formulations containing ketorolac have been used to manage postoperative pain and as ophthalmic solutions to treat ocular pain and inflammation. 1.Zhang, Y., Shaffer, A., Portanova, J., et al.Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 productionJ. Pharmacol. Exp. Ther.283(3)1069-1075(1997) |
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