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Tolperisone-d10(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tolperisone-d10(hydrochloride)图片
CAS NO:1185160-65-9
包装与价格:
包装价格(元)
500 μg电议
1mg电议

产品介绍
An internal standard for the quantification of tolperisone
Cas No.1185160-65-9
别名盐酸托哌酮 d10 (盐酸盐)
Canonical SMILESCC1=CC=C(C(C(CN2C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C2([2H])[2H])C)=O)C=C1.Cl
分子式C16H13D10NO.HCl
分子量291.9
储存条件Store at 2°C to 8°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tolperisone-d10is intended for use as an internal standard for the quantification of tolperisone by GC- or LC-MS. Tolperisone is a piperidine that acts as an inhibitor of voltage-gated sodium channels with an IC50value of 198 µM, for inhibition of peak sodium currents evoked by step depolarizations in dorsal root ganglion (DRG) neurons,in vitro.1Tolperisone acts as an antispastic agent that attenuates monosynaptic, disynaptic, and polysynaptic reflux response to dorsal root stimulationin vivo. Formulations containing tolperisone are used as analgesics and muscle relaxants.

1.Kocsis, P., Farkas, S., Fodor, L., et al.Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channelsJ. Pharmacol. Exp. Ther.315(3)1237-1246(2005)