| CAS NO: | 112208-01-2 |
| 包装: | 1mg |
| 市场价: | 1215元 |
| Cas No. | 112208-01-2 |
| 别名 | Pam3Cys-Ser-(Lys)4 TFA |
| 分子式 | C81H156N10O13S.3C2HF3O2 |
| 分子量 | 1852.33 |
| 溶解度 | DMSO : ≥ 50 mg/mL (26.99 mM) |
| 储存条件 | -20°C, away from moisture |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2[1]. Pam3CSK4 is a TLR1/2 heterodimer recognises triacylated lipopeptides[1].Pam3CSK4 (1 μg/mL) enhances the antibacterial functions of granulocyte macrophage-colony stimulating factor (GM-CSF) induced neutrophils to Methicillin-resistant Staphylococcus aureus (MRSA)[2]. Pam3CSK4 (5 mg/kg; i.p.; once a day for 9 days) alters brain, spleen and liver weights in neonatal mice[3]. [1]. Irvine KL, et al. The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6. Vet Res. 2013 Jul 4;44:50. |
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