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Pravastatin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Pravastatin图片
CAS NO:81093-37-0
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议
200mg电议

产品介绍
Pravastatin (CS-514) 是一种竞争性 HMG-CoA 还原酶抑制剂，可抑制甾醇合成，IC50 为 5.6 μM。
Cas No.81093-37-0
别名普伐他汀; CS-514
化学名(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
Canonical SMILESCCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)O
分子式C23H36O7
分子量424.53
溶解度≥ 14.05mg/mL in DMSO
储存条件Store at -20°C,protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pravastatin (CS-514) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.

Pravastatin (CS-514) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease[1].

References:
[1]. McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.