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DUBs-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DUBs-IN-3图片
CAS NO:924296-17-3
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
DUBs-IN-3 是一种有效的去泛素酶 (USP) 酶抑制剂,从参考化合物 22c 中提取,对 USP8 的 IC50 为 0.56 μM。
Cas No.924296-17-3
别名9-[(2-丙烯-1-氧基)亚氨基]-9H-茚并[1,2-B]吡嗪-2,3-二甲腈
化学名(E)-9-((allyloxy)imino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Canonical SMILESC=CCO/N=C1C2=CC=CC=C2C3=C\1N=C(C(C#N)=N3)C#N
分子式C16H9N5O
分子量287.28
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.

References:
[1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.