| CAS NO: | 57265-65-3 |
| 包装: | 10mg |
| 市场价: | 900元 |
| Cas No. | 57265-65-3 |
| 别名 | 钙调蛋白抑制剂,R 24571 |
| 化学名 | (S)-1-(bis(4-chlorophenyl)methyl)-3-(2-((2,4-dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazol-3-ium chloride |
| Canonical SMILES | ClC1=CC(Cl)=CC=C1[C@@H](C[N+]2=CN(C=C2)C(C(C=C3)=CC=C3Cl)C(C=C4)=CC=C4Cl)OCC(C(Cl)=C5)=CC=C5Cl.[Cl-] |
| 分子式 | C31H23Cl7N2O |
| 分子量 | 687.7 |
| 溶解度 | 100mM in ethanol, or in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Calmidazolium (chloride) is an inhibitor of calmodulin (CaM), inhibiting CaM-dependent phosphodiesterase and CaM-induced activation of erythrocyte calcium-transporting ATPase (IC50 = 0.15 and 0.35 μM, respectively).[1] Calmidazolium also inhibits an array of calcium-transporting ATPases, including those from heart and skeletal muscle (IC50 = 2.1 and 2.9 μM, respectively).[1] It also induces the influx of extracellular calcium through store-operated calcium channels (EC50 = 3 μM).[2],[3] Reference: |
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