9-(2,2-Dicyanovinyl)julolidine (9-(2,2-Dicyanovinyl)julolidine) 是一种分子转子和独特的荧光染料,可与微管蛋白和肌动蛋白结合,并在聚合时显着增加其荧光强度。
Cas No. | 58293-56-4 |
别名 | 9-(2,2-二氰乙烯基)久洛啶,9-(2,2-Dicyanovinyl)julolidine |
Canonical SMILES | N#C/C(C#N)=C\C1=CC2=C3N(CCC2)CCCC3=C1 |
分子式 | C16H15N3 |
分子量 | 249.3 |
溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 0.2 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 9-(2,2-Dicyanovinyl)julolidine (DCVJ) is a fluorogenic dye that is considered a fluorescent molecular rotor because its properties depend on the rotational relaxation of the molecule, which can be influenced by the viscosity of the solvent used. It has an excitation maximum at approximately 450 nm, and its emission is approximately 480 or 505 nm for low or high viscosity solvents, respectively. DCVJ has been used to study tubulin dynamics because its fluorescence increases when bound to tubulin sheets but is lower when bound to microtubules. |